Pdf hyperkeratotic palmoplantar lichen planus in a child. Lichen planus is an incurable and often chronic disease. Polyarteritis nodosa most commonly affects muscles, joints, intestines, nerves, kidneys, and skin. Hyperkeratotic plaques on the palms and solesdiagnosis. Involvement of palm and soles is thought to be uncommon in lp. Flegel disease is also known as hyperkeratosis lenticularis perstans.
Jan 29, 2018 hyperkeratotic hand eczema is uncommon. What are the signs and symptoms of hypertrophic lichen planus. Palmoplantar lichen planus presenting with vesiclelike papules. May 08, 2020 lichen planus also will tend to form on areas of skin injurytrauma. It is characterized by polygonal, flattopped, violaceous papules and plaques with overlying, reticulated, fine white scale wickhams striae, commonly affecting dorsal hands, flexural wrists and forearms, trunk, anterior lower legs and oral mucosa.
In its classic form, it presents with violaceous, scaly, flattopped, polygonal papules. Acrokeratosis verruciformis is a rare genodermatosis with an autosomal dominant mode of inheritance. A case of palmoplantar lichen planus mimicking secondary. Disease bioinformatics research of keratosis lichenoides chronica has been linked to keratosis, lichenoid eruptions, lichen planus, lichen disease, exanthema. Skip disorder list and go to main content disorders lichen nitidus lichen planopilaris lichen planus, actinic. Palmoplantar lichen planus is a rare, localized variant of lichen planus. I have two close relatives with lichen planus and have helped with their treatment for over ten years. Links abreu velez am, yi h, googe pb jr, mihm mc jr, howard ms. This chapter provides a practical overview of keratoderma, and is set out as below. Pathology outlines poikiloderma atrophicans vasculare. Cutaneous adverse effects of imatinib mesylate glivec are common and various types of skin eruptions have been reported. Flegel disease is a rare dermatosis characterized by asymptomatic hyperkeratotic papules predominantly on the dorsa of the feet and lower legs. Acrosyringeal lichen planus of palm gutte rm indian j.
Punctate palmoplantar hyperkeratosis type 3 dovemed. We present four unusual cases of palmoplantar lp and ln manifesting as hyperkeratotic plaques with pits. Although several clinical features of palmoplantar lichen planus may be seen, the erythematous scaly form is. Palmoplantar lichen planus, hyperkeratotic variant. Characteristics include generalized redness of the skin and severe.
Comment punctate hyperkeratosis of the palms and soles is a relatively rare disorder which has been rc volume 3 number i hyperkeratosis of palms and soles 45 july, 1980 fig. Palmoplantar lichen planus is a localized and uncommon variant of. Although the lesion was only on the foot and not on the hands, our cases was thought to be a single plaque lesion as a rare variant of palmoplantar lichen planus. Women who suffer from his condition may also witness some form of rashes in the lining of. The lesions are frequently covered with a lacy network of white scales. A synopsis of the lichen genus xanthoparmelia vainio hale ascomycotina, parmeliaceae, 1990, smithsonian institution, smithsonian contributions to botany, number 74. Lichen planus pemphigoides lpp, which is a rare autoimmune blistering mucocutaneous disease of the pemphigoid family of diseases, is characterized by the development of vesiculobullous lesions on or adjacent to the areas of lichen planus lp.
Varients of lichen planus are presented in figures 29. May 11, 2018 acrokeratosis verruciformis is a rare genodermatosis with an autosomal dominant mode of inheritance. A revision of the lichen genus hypotrachyna parmeliaceae in tropical america related titles. Mar 21, 2018 learn indepth information on hypertrophic lichen planus, its causes, symptoms, diagnosis, complications, treatment, prevention, and prognosis.
Various known morphological presentations of palmoplantar lichen planus pplp include hypertrophic variant, diffuse scaly variant, punctuate keratoses, diffuse keratoderma, erosive or ulcerative lesions, pigmented macular variant, vesicular lesions, keratotic plaques with pits and umbillicated papules. The earliest lesions had started twelve years earlier. Hyperkeratotic dermatitis of the palms springerlink. Keratoderma can be inherited, acquired, and rarely, paraneoplastic ie secondary to an internal malignancy. Squamous cell carcinoma arising in lichen planus hypertrophicus. Circumscribed violaceous erythema with associated telangiectasia, hypopigmentation and superficial atrophy occurs in posterior shoulders, back, buttocks, v shaped area of the anterior neck and chest. Palmoplantar lichen planus pplp is an uncommon, localized variant of lichen planus lp. Acrokeratosis verruciformis is a disorder of keratinization characterized by multiple flattopped, skincolored keratotic lesions resembling plane warts typically observed on the dorsum of the hands and feet. The study of hyperkeratosis has been mentioned in research publications which can be found using our bioinformatics tool below. Lichen nitidus mainly affects children and young adults. Porokeratoma is a recently described type of acanthoma containing the characteristic feature of porokeratosis.
Bullous lichen planus and lichen planus pemphigoides. Autoantibodies to melanocytes and characterization of melanophages in patients affected by a new variant of endemic pemphigus foliaceus. Palmoplantar keratoderma primary care dermatology society uk. Hywel williams, michael bigby, thomas diepgen, andrew herxheimer, luigi naldi. Subtle features like presence of violaceous border suggests lp and plugs within the pits suggest ln. Mar 03, 2008 patient presentation a 56yearold hispanic woman presented with numerous hyperkeratotic, hyperpigmented, small, firm papules that were coalescing into symmetric plaques on the bilateral distal arms and legs.
Aug 17, 2009 cutaneous adverse effects of imatinib mesylate glivec are common and various types of skin eruptions have been reported. It is typically located centrally or proximally in the palms. Lichen planus lpfrom the greek leichen, meaning tree moss, and the latin planus, meaning flatis a chronic idiopathic inflammatory dermatoses that commonly affects the skin, hair, nails, and mucosal membranes. We report a case of a 37yearold male with lichen planus who presented with multiple erythematous, scaly, hyperkeratotic papules on his palms and soles mimicking secondary syphilis. Lichen planus lp and lichen nitidus ln present with varied morphology on the palms and soles. Palmoplantar lp has varied morphological presentations apart from classically described yellowish hyperkeratotic papules and plaques. Histopathological examination revealed compact orthokeratosis, focal parakeratosis, hypergranulosis, irregular slightly sawtooth acanthosis with focal vacuolar alteration of basal layer with degeneration of basement membrane and few necrotic keratinocytes. A closeup view of hyperkeratotic papules found on the sole of the foot as described in fig. Clinical, histopathological, and ultrastructural features of a new clinical variant of porokeratosis mibelli pm are presented. Unilateral acrosyringeal lichen planus of palm gutte rm. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis. Lichen planus lp is a chronic inflammatory and immune mediated disease that affects the skin, nails, hair, and mucous membranes. Frontal fibrosing alopecia is a variant elderly women, along frontal hairline grahamlittlepiccardilassueur syndrome triad.
Palmoplantar lichen planus ppl is an uncommon type of lichen planus lp that exclusively affects the palms and soles. A case of palmoplantar lichen planus mimicking secondary syphilis. Skip disorder list and go to main content disorders lichen nitidus lichen planopilaris lichen planus, actinic lichen planus, annular lichen planus, bullous and pemphigoides. In our cases, there was only a single plaque lichen planus on the foot, a rather rare variant of lichen planus 7. The patient was diagnosed as a case of ppl by skin biopsy, and treated with acitretin. Lichen nitidus is a relatively rare, chronic skin eruption that is characterized clinically by asymptomatic, flattopped, skincolored micropapules see image below. Hersle k, mobacken h 1982 hyperkeratotic dermatitis of the palms. The patient indicated that her lesions were very pruritic and had slowly appeared. Palmoplantar lichen planus pplp is an uncommon, localized variant of lichen. Hyperkeratotic pitted plaques on the palms and soles.
Pdf palmoplantar keratoderma as a variant of lichn planus. A revision of the lichen genus hypotrachyna parmeliaceae. The disorder is thought to be caused by alterations in the membranecoating granules lamellar granules, odland bodies of the keratinocytes. This case describes a patient that presented with multiple papules on his hands and plantar feet that had previously been diagnosed as tinea manum and psoriasis. Because palmoplantar lesions are uncommon 57 and do not present with the classic violaceous, flattopped, polygonal papules and wickham striae. Microscopic findings and clinical course histologic examination of a hematoxylineosinstained biopsy specimen revealed hyperkeratosis, wedgeshaped hypergranulosis, irregular acanthosis, degenerative keratinocytes known as colloid or civatte bodies, and a bandlike. A diagnosis of palmar lichen nitidus, lp and pompholyx was thought and a skin biopsy was obtained from a representative lesion. It is characterised by redbrown papules with irregular horny scales located mainly on the top surface of the feet and lower legs. Palmoplantar lichen planus is a localized and uncommon variant of lichen planus which is mostly resistant to treatment.
Kertatoderma can be inherited, acquired, and rarely, paraneoplastic ie secondary to an internal malignancy. Lichen nitidus typically presents as shiny pinhead sized papules on the trunk and extremities, often affecting children and young adults. We report a solitary case of a patient, male aged 62, who developed disseminated verrucous nodules on the buttocks and the lower extremities 3 years before diagnosis. Clinical input is often very helpful in making a diagnosis histopathologically. Otherwise, she enjoyed good past health with normal development.
We report a case of a 50yearold man who had palmoplantar hyperkeratotic papules and plaques. Morphealichen sclerosus et atrophicus overlap is characterized by both lesions of morphea and lichen sclerosus et atrophicus, most commonly seen in women. Case study palmoplantar keratoderma as a variant of lichen. Progressive symmetric erythrokeratoderma presenting as. Patient presentation a 56yearold hispanic woman presented with numerous hyperkeratotic, hyperpigmented, small, firm papules that were coalescing into symmetric plaques on the bilateral distal arms and legs. Lichen planus is a common inflammatory papulosquamous disorder affecting skin, mucous membranes, nails and hairs variably. The study of keratosis lichenoides chronica has been mentioned in research publications which can be found using our bioinformatics tool below. She also complained of multiple brown reticulated macules distributed symmetrically over her upper back. Multiple clinical presentations of pplp may be seen, the erythematous scaly form is most common and other clinical presentations include vesiclelike and petechialike lesions, which are rare variants. Lichen planus also will tend to form on areas of skin injurytrauma. Generally, the timing of development of the signs and symptoms are important in ensuring an accurate diagnosis. Lichen planus klassischer typ altmeyers enzyklopadie. Learn vocabulary, terms, and more with flashcards, games, and other study tools.
It is very similar to kyrle disease and has been regarded as a variant of kyrle disease, however its. It is characterized by volar, often bilateral, and symmetric hyperkeratosis of the skin. Cutaneous manifestation of a diverse group of diseases may occur as inherited disorder, with downs syndrome or after ingestion of drugs 80% are benign type, either autosomal dominant or associated with tissue resistance to insulin, including diabetes, obesity and cushings disease. Illustrations of the various lesions and details of the history, which was carried to. Progressive symmetric erythrokeratoderma presenting as hyperkeratotic plaques in a young girl mym wat, kh yeung, kc yau case report a 15yearold young girl presented with multiple hyperkeratotic plaques since 4 years old. Palmoplantar lichen planus lp, hyperkeratotic variant.
Treatment modalities of palmoplantar lichen planus. Lichen planus is a common inflammatory dermatoses palmplantar lichen planus is an uncommon variant of lichen planus. Please remove adblock adverts are the main source of revenue for dovemed. Hyperkeratotic pitted plaques on the palms and soles khandpur. Lichenoid drug eruption with palmoplantar hyperkeratosis. Palmoplantar keratoderma is a term used to define a marked thickening of the skin on the palms and soles, either as a focal entity, or diffuse.
Response to oral acitretin in lichen amyloidosis vasani rj. In this prototypical form, it rarely presents a diagnostic challenge being characterized by distinctive clinical and histopathologic findings. We report here a 57yearold man who presented with lichen planuslike lesions on his extremities and palmoplantar hyperkeratosis due to the use of imatinib mesylate for chronic myeloid leukaemia. Lpp primarily affects the skin, and oral involvement alone is rare. Typically, polyarteritis nodosa is treated with medications that suppress the immune system, such as prednisone and cyclophosphamide. Acrokeratoelastoidosis ake is a rare, benign skin condition, wherein there is warty papules affecting the hands and feet, typically on the sides. If you are looking for something that cure this ailment then your search will be fruitless. Lichen planus lichen ruber planus verein lichen sclerosus. A synopsis of the lichen genus xanthoparmelia vainio.
Lichen planus is a common skin disease, affecting 0. Histopathological examination revealed compact orthokeratosis, focal parakeratosis, hypergranulosis, irregular slightly sawtooth acanthosis with focal vacuolar alteration of basal layer with degeneration of basement membrane and few. Disease bioinformatics research of hyperkeratosis has been linked to keratosis, dermatologic disorders, palmoplantar keratosis, hyperplasia, carcinoma. Inflammation of the arteries can lead to inadequate blood supply and permanent damage to organs. The topic punctate palmoplantar hyperkeratosis type 3 you are seeking is a synonym, or alternative name, or is closely related to the medical condition acrokeratoelastoidosis. The rashes created by the infection are characterized with flat topped and manysided bumps which grow together to form scaly patches on the skin.
Parakeratotic hyperkeratosis definition of parakeratotic. Nonscarring alopecia of pubic and axillary hair with spiny follicular papules kp like. Nekam diseasekeratosis lichenoides chronica rooks textbook. Hyperkeratotic palmoplantar lichen planus in a child. An autoimmune disease that is characterized by spontaneous inflammation of the arteries and can affect any organ of the body. There was a yellow to brown thick symmetric hyperkeratosis of the palms and soles, including. Lichenoid drug eruption with palmoplantar hyperkeratosis due. Lichen planus can be described as a recurrent rash which occurs from inflammation. The current case describes palmoplantar lichen planus, a rare variant of this disease that can easily be misdiagnosed. Nov 20, 2019 lichen nitidus is a relatively rare, chronic skin eruption that is characterized clinically by asymptomatic, flattopped, skincolored micropapules see image below. Jul 06, 2012 lichen planus lp is a pruritic, benign, papulosquamous, inflammatory dermatosis of unknown etiology that affects either or all of the skin, mucus membrane, hair and nail. Although several clinical features of palmoplantar lichen planus may be seen, the erythematous scaly form is most common. Two years ago i reported a case of poikiloderma atrophicans vasculare. This is known as the isomorphic response or koebner phenomena.